Apotek Hotel is a stylish boutique hotel located in the very heart of Reykjavik´s most prestigious shopping, entertainment, and cultural district. The historical building formerly housed the pharmacy Reykjavikur Apotek and is widely considered to be one of the most remarkable buildings in Reykjavik.

Guðjón Samúelsson, a former State Architect of Iceland, designed the building in 1917. Guðjón built some of Iceland´s most renowned buildings such as the National Theater building, Hotel Borg, Akureyrarkirkja church, and Hallgrímskirkja church.